Dengue combo test

Key Benefits

  • Dengue  fever NS1 antigen IGG IGM Antibody combo test kit

Application

  • Dengue virus infection

Customized

  • IVD device contract manufacturing like OEM ODM
Category:

The DVOT Dengue combo test kit advantage

The dengue combo test kit has 3 big advantages:

  1. Immunochromatography, double antibody sandwich method. Qualitative detection of dengue virus NS1 antigen in human whole blood, serum, or plasma, with more accurate test results
  2. Good reactivity against all four dengue virus serotypes
  3. It does not cross-react with positive samples of Japanese encephalitis, measles, rubella, influenza A, epidemic meningitis, hepatitis B virus, AIDS, etc.
  4. Dengue Rapid Test Kit’s price is cheap.

What is a dengue combo test?

The Dengue Combo Test is an IVD device to detect dengue virus infection in patients. It combines two diagnostic methods: NS1 antigen detection and IgM/IgG antibody detection to accurately detect dengue virus infection in both early and late stages.

  1. NS1 antigen is detectable early, usually within 1-7 days after infection, indicating that the virus is replicating.
  2. IgM and IgG antibodies help identify immune responses, with IgM indicating recent infection and IgG indicating past infection or late infection。

The Dengue Combo Test can be used for rapid diagnosis and help guide treatment decisions, especially in dengue-endemic areas like Malaysia, Thailand, Philippines, Argentina, Brazil, Puerto Rico, Bangladesh, Pakistan, Hong Kong, Mexico, Peru, etc.

What is the most accurate test for dengue?

The most accurate dengue diagnostic test often depends on when during infection the test is taken. Here are the main tests used for dengue:

  1. Dengue NS1 Antigen Test (Early Detection)
    – Best for: Early diagnosis (1-5 days before onset of illness).
    – Accuracy: High sensitivity in the first few days of dengue fever (acute phase).
    – Details: Detects the presence of NS1 protein (a nonstructural protein of the dengue virus) in the blood. It can confirm infection before the body’s immune system produces antibodies.
  2. RT-PCR (Reverse Transcription Polymerase Chain Reaction) (Most Accurate Early Test)
    – Best for the First week of symptom onset.
    – Accuracy: Highly sensitive and specific.
    – Details: Detects the presence of dengue virus nucleic acid in the blood against dengue virus genetic material (RNA).
  3. IgM and IgG Antibody Tests (Late Detection)
    – Best for: First 4-5 days after symptom onset (tests IgM); IgG detects past infection.
    – Accuracy: Can be used to confirm recent or past infection.
    – Details: IgM antibodies are detectable in the blood approximately 4-5 days after symptom onset, indicating a recent infection. IgG antibodies appear later, indicating current or past infection.
  4. ELISA (Enzyme-Linked Immunosorbent Assay) (Serological Test)
    – Best for: Detecting antibodies, especially in the later stages (after the acute phase).
    – Accuracy: Good, but not as accurate as RT-PCR, good for early detection.
    – Details: Typically used to detect IgM and IgG antibodies to confirm dengue fever after the acute infection period.

What does a positive dengue antibody test mean?

1. IGM positive indicates recent infection with dengue virus;
2. IgG positive indicates past infection with dengue virus and recovery.